We’re inviting you to take part in a study for individuals with Acid Reflux, Heartburn or GERD (gastroesophageal reflux disease). All study-related visits, tests and the investigational medication will be provided at no cost. In addition, you may receive compensation for time and travel. No health insurance is required.
The RECLAIM Study is evaluating an investigational medication to learn if it may help prevent heartburn or acid reflux symptoms when taken along with a proton pump inhibitor (PPI) medication.
Gastroesophageal reflux disease (GERD) is a condition in which acid from the stomach regurgitates or brings up the stomach contents into the esophagus (tube that connects the throat and stomach) or back of the throat. GERD encompasses other terms that people use to describe their symptoms, such as acid reflux or heartburn.1
It is estimated that around 25% of North Americans and Europeans have gastroesophageal reflux disease (GERD).2 Risk factors for developing Acid Reflux include obesity, pregnancy, the consumption of certain foods or beverages, eating late at night, use of certain medications, and smoking.3
Symptoms of GERD can interfere with everyday life. These may include:
In severe and medication intolerant cases, surgery may be recommended.
The RECLAIM Study is evaluating an investigational medication to learn if it may help prevent heartburn or reflux symptoms when taken along with a proton pump inhibitor (PPI) medication.
What happens if I sign up? We will match you to a research study location in your area that needs volunteers with Acid Reflux or heartburn (otherwise known as gastroesophageal reflux disease, GERD) or notify you when one becomes available. The study team will then contact you and you may have the opportunity to participate if qualified.
If you think you might like to participate in the RECLAIM Study or would like more information, please enter your information below so we can see if you may qualify and can contact you about the studies. Keep in mind that participation is entirely voluntary. If you do decide to take part in a study, you may change your mind about participating at any time.
The RECLAIM Study will enroll about 1320 participants with Acid Reflux or Heartburn (otherwise known as gastroesophageal reflux disease, GERD) at approximately 200 study clinics in the United States and Canada.
Participants will receive all study-related visits, tests, and investigational drug or placebo from a dedicated medical team at no cost.
The study will include approximately 5 visits to a study clinic in your location, one phone call, and your participation will last up to 17 weeks. The study staff will work with you to find convenient times for your visits.
Volunteers who qualify to take part in the study may receive compensation for time and travel.
In this study, researchers will be evaluating an investigational medication for Acid Reflux or Heartburn.
You may be able to take part in the study if:
All study-related care is provided by clinical research sites.
A clinical research study (also called a clinical trial) is conducted to learn whether a drug, treatment, or method is safe and effective for people who have certain ailments or illnesses. Clinical research studies follow strict scientific standards to ensure they produce the best data available for health care decision making. All medications must be tested in clinical research studies before they can be approved and prescribed to patients.
In this study, local doctors are investigating a medication to learn if it may help heartburn or acid reflux symptoms when taken along with proton pump inhibitor (PPI) medication. They want to compare the study drug to placebo, which looks like the study drug, but contains no active ingredients.
The results of this study will provide more information about the effectiveness and safety of the investigational medication to treat Acid Reflux or Heartburn (otherwise known as gastroesophageal reflux disease, GERD).
Eligible participants will be randomly assigned (like flipping a coin) to receive either the investigational medication or placebo. To prevent opinions about the study drug from affecting the study results, the study is designed so that participants, the study doctor, and the study staff will not know the study drug assignments. However, in the event of an emergency, this information can be provided.
Participants will take their study drug twice a day for approximately 8 weeks. Participants will also be asked to visit the study clinic up to 5 times for tests and evaluations. Total study participation could last up to 17 weeks which includes screening for eligibility, treatment, and follow-up.
Volunteers who qualify to take part in the study will receive compensation for study-related time and travel. Please discuss this with the study team when they contact you.
There is no cost to participate in the RECLAIM Study. If you qualify, all study-related visits, tests, study medication or placebo will be provided at no cost. If you decide to take part:
The research team will be able to explain more about what the RECLAIM Study will involve, and it is up to you to decide if you want to take part. Participation in this study is voluntary. Whether or not you decide to participate in this study will not affect your current or future relationships with your doctors. If you decide to participate, you are free to withdraw at any time without affecting those relationships.
Throughout the study, you will remain on your daily PPI (proton pump inhibitor) medication. In the RECLAIM Study, researchers will evaluate the safety and efficacy of the study medication and placebo in treating the symptoms of heartburn and acid reflux when taken along with a proton pump inhibitor (PPI) medication.
We match you to a research center within a close travel distance from your home. If we are not running the study in your area currently, with your permission, we will keep you in our database and reach out once a study in your area becomes available. If, at any time, you decided you no longer want your information stored, you can opt out and we will delete your details.
The study doctor and staff will handle your personal health information in a confidential manner. Your personal health information includes both your study data and original medical records. To ensure your privacy, your name and other identifying information won’t be attached to any records or samples released for research purposes. Instead, the records and samples will only be identified by a code.